Quinolone antibiotics literature review

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An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections , and antibiotic medications are widely used in the treatment and prevention of such infections. A limited number of antibiotics also possess antiprotozoal activity. However, both classes have the same goal of killing or preventing the growth of microorganisms, and both are included in antimicrobial chemotherapy. Antibiotics have been used since ancient times.
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Quinolone antibiotic

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Antibiotic - Wikipedia

George M. Eliopoulos, Lisa L. Maragakis, Trish M. Multidrug-resistant Acinetobacter baumannii is recognized to be among the most difficult antimicrobial-resistant gram-negative bacilli to control and treat.
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What Clinicians Should Know About the QT Interval

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A quinolone antibiotic is a member of a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. Nearly all quinolone antibiotics in use are fluoroquinolones , which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria. One example is ciprofloxacin , one of the most widely used antibiotics worldwide. Fluoroquinolones are often used for genitourinary infections and are widely used in the treatment of hospital-acquired infections associated with urinary catheters. In community-acquired infections, they are recommended only when risk factors for multidrug resistance are present or after other antibiotic regimens have failed.
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