Malignant pleural effusion case study

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In this study, we aimed to examine the clinical value of the pleural effusion PE biomarkers, soluble mesothelin-related peptide SMRP , cytokeratin 19 fragment CYFRA 21—1 and carcinoembryonic antigen CEA , and the utility of combining chest computed tomography CT findings with these biomarkers, in diagnosing malignant pleural mesothelioma MPM. We conducted a retrospective cohort study in a single center. Consecutive patients with undiagnosed pleural effusions who underwent PE analysis between September and August were reviewed. Combination of these biomarkers helped to rule out MPM effectively among patients at high risk of suffering MPM and would be valuable especially for old frail patients who have difficulty in undergoing invasive procedures such as thoracoscopy. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

[Discussion on registry study of acupuncture-moxibustion for malignant pleural effusion]

Malignant pleural effusion (2) - Radiology at St. Vincent's University Hospital

The journal publishes 6 issues per year, mainly about respiratory system diseases in adults and clinical research. This work can range from peer-reviewed original articles to review articles, editorials, and opinion articles. The journal is printed in English, and is freely available in its web page as well as in Medline and other databases. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published.

Malignant Pleural Effusion: Diagnosis and Management

A 34 year-old woman with a history of heavy alcohol use presents to the emergency room complaining of increasing shortness of breath and right-sided chest pain. Her past medical history is remarkable for several prior episodes of pancreatitis, likely secondary to her chronic alcohol use. A chest x-ray is performed and is shown below:. She initially undergoes thoracentesis for symptom relief but studies are not performed on the fluid.
Metrics details. Malignant pleural effusions MPE are a common terminal pathway for many cancers, with an estimated United States incidence of more than , cases per year. The development of an effective targeted therapy represents a pressing unmet need. This commentary focuses on how cellular and humoral components condition the pleural space as a tumor-promoting, wound-healing environment.
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