Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: mmwrq cdc. Type Accommodation and the title of the report in the subject line of e-mail. Cases of a newly recognized illness known as toxic-shock syndrome 1 have recently been reported to CDC by state health departments in Wisconsin, Minnesota, Illinois, Utah, and Idaho. Physicians in 8 other states have reported individual cases to CDC or to investigators at the University of Colorado, Denver.
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In response to case reports of toxic shock syndrome, six case-comparison studies were done in Early cases were predominantly in menstruating women, and the use of tampons was strongly associated with the onset of illness. Because of the widespread publication of this finding, the case-comparison studies had problems due to differential ascertainment and recall bias. However, the number of cases among women was so great and the relation with tampon use so marked that unreasonable assumptions are necessary if the results are to be attributed to these biases. The studies show the power of epidemiologic methods, even given the unfavorable circumstance of an uncommon condition, associated with a common practice. Although the absolute risk of toxic shock syndrome is small, tampon users have more than a tenfold excess risk of the condition over women not using tampons, and the use of tampons is an adequate explanation for the excess risk of women over men.
From the way she runs on the basketball court, year-old Marie Harf does not look like a teenager who was gravely ill last spring. Overcome with fever and nausea, she had to leave her high school prom in May. She was rushed to the hospital the next day while a life-threatening illness quietly spread through her young body.
The authors report a case of near-fatal sepsis with multiorgan failure resulting from a Staphylococcal tampon-associated toxic shock syndrome, requiring a lengthy critical care admission. Successful treatment of this condition focuses on early identification, source control, and administration of antimicrobial agents. Intravenous immunoglobulin therapy used early may prevent widespread tissue necrosis. A year-old Caucasian schoolgirl presented to the Emergency Department ED complaining of a single day history of lower abdominal pain, muscle aches, diarrhoea, and vomiting.